Rabphilin 3A Antibody

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Western Blot: Rabphilin 3A Antibody [NB300-735]

Product Details

Summary
Reactivity Rt, Hu, Mu, Bv, Ca, PmSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

Rabphilin 3A Antibody Summary

Immunogen
Synthetic peptide corresponding to amino acid residues from the C-terminal region of rabphilin 3A.
Specificity
Specific for the ~82k rabphilin 3A protein.
Predicted Species
Human (100%), Mouse (100%), Primate (100%), Bovine (100%), Canine (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
RPH3A
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:1000

Reactivity Notes

It is anticipated that the antibody will react with mouse, human, bovine, canine and non-human primate tissue based on the fact that these species have 100% homology with the amino acid sequence used as antigen.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
10mM HEPES (pH 7.5), 0.15M NaCl, 0.1 mg/ml BSA and 50% Glycerol
Preservative
No Preservative
Purity
Immunogen affinity purified

Alternate Names for Rabphilin 3A Antibody

  • Exophilin-1
  • KIAA0985exophilin-1
  • rabphilin 3A homolog (mouse)
  • rabphilin
  • rabphilin-3A

Background

Rabphilin-3A is a peripheral membrane protein that binds Ca2+ and phospholipids and is attached to synaptic vesicle membranes (Geppert et al., 1994; Li et al., 1994). The expression of rabphilin 3A is reduced in an animal model of Huntington's disease (Smith et al., 2005). Rabphilin can be phosphorylated at Ser234 by both CAM kinase II and PKA and this phosphorylation has been suggested to regulate neuronal activity during development in a synapse-specific manner (Fykse et al., 1995; Foletti and Scheller, 2001).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol RPH3A
Entrez
Uniprot