RAB6B Antibody

Western Blot: RAB6B Antibody [24320002] - Samples: Lane 1, Marker [kDa]: 250, 130, 95, 72, 55, 36, 28, 17, 11 Lane 2, RT-4 Lane 3, U-251MG sp Lane 4, Human Plasma Lane 5, Liver Lane 6, Tonsil , Target weight [kDa]: 23 Validation score: 2 Validation description: Supportive - Band of predicted size in kDa (+/-20%) with additional bands present.

Immunohistochemistry: RAB6B Antibody [24320002] - Most normal tissue showed weak to moderate cytoplasmic and occasional membranous positivity. Parts of the gastrointestinal tract and Purkinje cells were strongly stained. Malignant cells were in most cases weakly stained or negative. Malignant gliomas and fractions of the malignant melanomas, renal and testicular cancers showed moderate positivity. Image and statement courtesy of the Human Protein Atlas (HPA).

ELISA: RAB6B Antibody [24320002]

Product Discontinued

RAB6B Antibody Summary

• Immunogen: This antibody is specific for the C Terminus Region of the target protein.
• Specificity: This product is specific for Human RAB6B.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: RAB6B
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Western Blot 1:5000-1:20000
• Application Notes: This antibody is useful in ELISA, Immunohistochemistry-Paraffin and Western Blot.

Reactivity Notes

Human.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20mM Potassium Phosphate (pH 7.0) and 0.15M NaCl
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Notes

Manufactured by SDIX's proprietary Genomic Antibody Technology™. GAT FAQs.

Alternate Names for RAB6B Antibody

• RAB6B, member RAS oncogene family
• ras-related protein Rab-6B
• small GTPase RAB6B
• small GTP-binding protein

Background

RAB6B seems to have a role in retrograde membrane traffic at the level of the Golgi complex. RAB6B may function in retrograde tansport in neuronal cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for RAB6B Antibody (24320002)(2)

Publications using 24320002

• Garrison C, Lastwika K, Zhang Y et al. Proteomic Analysis, Immune Dysregulation, and Pathway Interconnections With Obesity J Proteome Res. 2017-01-06 [PMID: 27769113] (MiAr)
  
  Details:
  Analysis is performed on plasma proteomic data to identify how obesity can alter pathways and to highlight the risk factor for disease in subjects with a high body mass index.
• Rho JH, Lampe PD. High-throughput screening for native autoantigen-autoantibody complexes using antibody microarrays J Proteome Res. 2013-05-03 [PMID: 23541305] (MiAr)
  
  Details:
  A novel method using antibody microarrays is used to detect autoantibody-antigen complexes that can potentially be useful for detection and characterization of diseases.

FAQs for RAB6B Antibody (24320002). (Showing 1 - 1 of 1 FAQs).

1. Does this antibody crossreact with Rab6A? Which corresponding amino acids in the C-terminal were used to make this antibody?
   • Unfortunately the cross reactivity with Rab6A has not been tested. The amino acid range of the immunogen used to create the antibody was 119-225.

Bioinformatics

• Gene Symbol: RAB6B
• Uniprot:
  • Q9NRW1(Human)