Human Protein phosphatase 1F ELISA Kit (Colorimetric)

ELISA: Human Protein phosphatase 1F ELISA Kit (Colorimetric) [NBP2-60587] - Standard curve.

• Reactivity: Hu
• Applications: ELISA
• Suitable Sample Type: Serum, Plasma, Cell Culture
• Standard Curve Range: 1.56 - 400 ng/mL (example only; lot dependent)

Human Protein phosphatase 1F ELISA Kit (Colorimetric) Summary

• Description: This assay employs a quantitative enzyme immunoassay technique that measures the specified antigen in samples.
• Standard Curve Range: 1.56 - 400 ng/mL (example only; lot dependent)
• Assay Type: Sandwich ELISA
• Kit Type: ELISA Kit (Colorimetric)
• Gene: PPM1F

Applications/Dilutions

• Dilutions:
  • ELISA
  • Sandwich ELISA

Packaging, Storage & Formulations

• Storage: Storage of components varies. See protocol for specific instructions.

Alternate Names for Human Protein phosphatase 1F ELISA Kit (Colorimetric)

• Ca(2+)/calmodulin-dependent protein kinase phosphatase
• CaMKPaseCaM-kinase phosphatase
• EC 3.1.3.16
• FEM-2
• hFEM-2
• KIAA0015POPX2CAMKP
• Partner of PIX 2
• PP2C phosphatase
• Protein fem-2 homolog
• protein phosphatase 1F (PP2C domain containing)
• protein phosphatase 1F
• protein phosphatase, Mg2+/Mn2+ dependent, 1F

Background

Protein phosphatase 1F is encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis. An alternatively spliced transcript variant has been identified, but its full-length nature has not been determined. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: PPM1F