Prostaglandin I2 Synthase Antibody Pair

Product Discontinued

Prostaglandin I2 Synthase Antibody Pair Summary

• Description: Quality control test: Immunoprecipitation-Western Blot (IP-WB). This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
  
  
• Antibody pair for IP: rabbit polyclonal anti-PTGIS (300 ul)
• Antibody pair for WB: mouse purified polyclonal anti-PTGIS (50 ug)
• Clonality: Polyclonal
• Gene: PTGIS
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Prostaglandin I2 Synthase Antibody Pair

• CYP8
• CYP8A1
• CYP8A1PTGI
• CYP8prostacyclin synthase
• EC 5.3.99.4
• MGC126858
• MGC126860
• PGIS
• PGIScytochrome P450, family 8, subfamily A, polypeptide 1
• Prostacyclin Synthase
• prostaglandin I2 (prostacyclin) synthase
• Prostaglandin I2 synthase
• PTGI
• PTGIS

Background

PTGIS encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: PTGIS