Prostaglandin I2 Synthase Products

Antibodies
Prostaglandin I2 Synthase Ant ...
Prostaglandin I2 Synthase Antibody...
MAB7788
Species: Hu
Applications: WB, Simple Western
Host: Mouse Monoclonal
Prostaglandin I2 Synthase Ant ...
Prostaglandin I2 Synthase Antibody
AF7788
Species: Hu
Applications: WB
Host: Sheep Polyclonal
Prostaglandin I2 Synthase Ant ...
Prostaglandin I2 Synthase Antibody
NBP1-85359
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Antibody Pairs
Prostaglandin I2 Synthase Ant ...
Prostaglandin I2 Synthase Antibody...
H00005740-PW1
Species: Hu
Applications: WB, IP
Lysates
Prostaglandin I2 Synthase Ove ...
Prostaglandin I2 Synthase Overexpr...
H00005740-T01
Species: Hu
Applications: WB
Prostaglandin I2 Synthase Ove ...
Prostaglandin I2 Synthase Overexpr...
NBL1-14940
Applications: WB
Proteins
Prostaglandin I2 Synthase Rec ...
Prostaglandin I2 Synthase Recombin...
H00005740-P01
Species: Hu
Applications: WB, ELISA, PA
Prostaglandin I2 Synthase Par ...
Prostaglandin I2 Synthase Partial ...
H00005740-Q01
Species: Hu
Applications: WB, ELISA, PA
Prostaglandin I2 Synthase Rec ...
Prostaglandin I2 Synthase Recombin...
NBP1-85359PEP
Species: Hu
Applications: AC
RNAi
Prostaglandin I2 Synthase RNA ...
Prostaglandin I2 Synthase RNAi
H00005740-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

PTGIS encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Product By Gene ID 5740
Alternate Names
  • MGC126858
  • EC 5.3.99.4
  • Prostaglandin I2 synthase
  • CYP8prostacyclin synthase
  • PGIScytochrome P450, family 8, subfamily A, polypeptide 1
  • CYP8A1PTGI
  • MGC126860
  • prostaglandin I2 (prostacyclin) synthase

PTMs for Prostaglandin I2 Synthase

Learn more about PTMs related to Prostaglandin I2 Synthase.

Methylation
Demethylation
Oxidation

Bioinformatics Tool for Prostaglandin I2 Synthase

Discover related pathways, diseases and genes to Prostaglandin I2 Synthase. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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