PP2C beta/PPM1B Antibody (k1B1) [DyLight 650]

Product Discontinued

PP2C beta/PPM1B Antibody (k1B1) [DyLight 650] Summary

• Immunogen: Recombinant human PPM1B (288-479aa) purified from E. coli
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: PPM1B
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Flow Cytometry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein G purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for PP2C beta/PPM1B Antibody (k1B1) [DyLight 650]

• EC 3.1.3.16
• MGC21657
• PP2C beta
• Pp2c2
• PP2CB
• PP2C-beta
• PP2C-beta-X
• PP2CBmagnesium-dependent, beta isoform
• PPM1B
• protein phosphatase 1B
• Protein phosphatase 2C isoform beta
• protein phosphatase 2C-like protein
• protein phosphatase, Mg2+/Mn2+ dependent, 1B

Background

PPM1B is encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PPM1B