POFUT2 Antibody (OTI3A12) [DyLight 650]

• Reactivity: Hu, Mu, Rt
• Applications: WB, Flow
• Clone: OTI3A12
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 650

POFUT2 Antibody (OTI3A12) [DyLight 650] Summary

• Immunogen: Full length recombinant protein of human POFUT2 (NP_598368) produced in HEK293T cells.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: POFUT2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for POFUT2 Antibody (OTI3A12) [DyLight 650]

• C21orf80
• chromosome 21 open reading frame 80
• FUT13EC 2.4.1.221
• GDP-fucose protein O-fucosyltransferase 2
• KIAA0958
• O-FucT-2
• Peptide-O-fucosyltransferase 2
• protein O-fucosyltransferase 2

Background

Fucose is typically found as a terminal modification of branched chain glycoconjugates, but it also exists in direct O-linkage to serine or threonine residues within cystine knot motifs in epidermal growth factor (EGF; MIM 131530)-like repeats or thrombospondin (THBS; see MIM 188060) type-1 repeats. POFUT2 is an O-fucosyltransferase that use THBS type-1 repeats as substrates (Luo et al., 2006 [PubMed 16464857]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: POFUT2