PIB5PA Antibody

Immunohistochemistry-Paraffin: INPP5E Antibody [NB110-55574] - Analysis of anti-INPP5J / PIB5PA antibody with human kidney.

Product Discontinued

PIB5PA Antibody Summary

• Immunogen: Synthetic 18 aa peptide from near C-terminus of human PIB5PA.
• Epitope: Near C terminus
• Specificity: Human PIB5PA. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except PPP1R3A (50%).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: INPP5J
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 6 ug/ml

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for PIB5PA Antibody

• A
• inositol polyphosphate 5-phosphatase J
• inositol polyphosphate-5-phosphatase J
• phosphatidylinositol 4,5-bisphosphate 5-phosphatase A
• PIPP

Background

PIB5PA, also referred to as Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A, has a long isoform that is 1,006 amino acids in length and 107 kDa, and two shorter isoforms that are 639 and 638 amino acids long. It is known that PIB5PA converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4-phosphate, and it is thought that PIB5PA may mediate the function of plasma membrane proteins. Research is currently being conducted on PIB5PA in relation to several diseases and disorders including breast cancer, Guillain-Barre syndrome, developmental disorders and Autoimmune Lymphoproliferative Syndrome. PIB5PA has also been shown to have interactions with INPP1, PTEN, ITPK1, INPP4A and ITPKA in pathways such as lipid metabolism and lipoprotein metabolism.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: INPP5J
• Entrez:
  • 56623(Human)
• Uniprot:
  • Q9NRR6(Human)