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Phospho-GSK-3 alpha/beta (S21/S9) DuoSet IC ELISA, 2 Plate

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications ELISA
Conjugate
Biotin

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Biotin
DYC2630-5
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Phospho-GSK-3 alpha/beta (S21/S9) DuoSet IC ELISA, 2 Plate Summary

Modification
p Ser196, p Ser21
Source
N/A
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publication using DYC2630-2.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Phospho-GSK-3 alpha/beta (S21/S9) DuoSet IC ELISA, 2 Plate

  • DKFZp686D0638
  • EC 2.7.11
  • EC 2.7.11.26
  • glycogen synthase kinase 3 alpha
  • glycogen synthase kinase-3 alpha
  • GSK-3 alpha
  • GSK-3 alpha/beta

Background

GSK-3 is a Ser/Thr kinase first identified as an inactivator of Glycogen Synthase. GSK-3 acts as a multifunctional downstream switch that determines the output of numerous signaling pathways. There are two mammalian GSK-3 isoforms encoded by distinct genes, GSK-3 alpha and GSK-3 beta, which are structurally similar, but functionally non-identical. GSK-3a is inhibited by phosphorylation at S21 by Akt and other kinases. GSK-3 alpha and GSK-3 beta share 85% amino acid identity. Dysregulated GSK-3 has been implicated in several diseases including type II diabetes, Alzheimer's disease, bipolar disorder, and cancer.

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Phospho-GSK-3 alpha/beta (S21/S9) DuoSet IC ELISA, 2 Plate
Species: Hu, Mu, Rt
Applications: ELISA

Publications for GSK-3 alpha/beta (DYC2630-2)(1)

We have publications tested in 1 confirmed species: Human.


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