PER2 Antibody

Immunohistochemistry-Paraffin: PER2 Antibody [NBP2-24596] - Analysis of PER2 in FFPE human brain tissue using an isotype control (top left) and this antibody (bottom left, right) at 5 ug/ml.

Product Discontinued

PER2 Antibody Summary

• Immunogen: A portion of amino acids 1010-1060 of human PER2 was used as the immunogen.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PER2
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 5 ug/ml

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 0.2 ml PBS and 0.05% BSA
• Preservative: 0.05% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Protein A purified

Alternate Names for PER2 Antibody

• Circadian clock protein PERIOD 2
• FASPS
• hPER2
• KIAA0347period 2
• period (Drosophila) homolog 2
• period circadian protein 2
• period circadian protein homolog 2
• period homolog 2 (Drosophila)

Background

PER2 is a member of the Period protein family and a mammalian homolog of the Drosphilia period gene. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. Strong PER2 expression in the suprachiasmatic nuclei of the mamalian brain indicates that the PER gene functions in the circadian clock with PER2 being a component of the circadian oscillator. PER2 shares a 40% homology with PER1 including the protein dimerization PAS domain.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for PER2 Antibody (NBP2-24596)(1)

Publication using NBP2-24596

• Xiong H, Yang Y, Yang K et al. Loss of the clock gene PER2 is associated with cancer development and altered expression of important tumor-related genes in oral cancer. Int J Oncol 2018-01-01 [PMID: 29115399] (Human)

Bioinformatics

• Gene Symbol: PER2
• Uniprot:
  • O15055(Human)