PDE4B Antibody


Western Blot: PDE4B Antibody [NBP1-33637] - Western blot analysis of PDE4B on IMR32 (Lane A) and HCT116 (Lane B) lysates using NBP1-33637 at a dilution of 1:1000. 30ug whole cell lysate loaded on 7.5% SDS PAGE gel.
Western Blot: PDE4B Antibody [NBP1-33637] - Sample (30 ug of whole cell lysate) A: NT2D1 B: PC-3 7. 5% SDS PAGE, antibody diluted at 1:1000.

Product Details

Reactivity HuSpecies Glossary
Applications WB
0.72 mg/ml

Order Details

PDE4B Antibody Summary

Recombinant fragment corresponding to a region within amino acids 489 and 736 of PDE4B (Uniprot ID#Q07343)
Predicted Species
Primate (100%)
Immunogen affinity purified
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Packaging, Storage & Formulations

Store at -20C. Avoid freeze-thaw cycles.
1XPBS, 10% Glycerol (pH7).
0.01% Thimerosal
0.72 mg/ml
Immunogen affinity purified

Reactivity Notes

Tested in human. Predicted cross-reactivity based on sequence identity: Rhesus Monkey (100%). Not yet tested in any other species.

Alternate Names for PDE4B Antibody

  • cAMP-specific (phosphodiesterase E4 dunce homolog
  • cAMP-specific 3'-5'-cyclic phosphodiesterase 4B
  • cAMP-specific phosphodiesterase-4 B isoform
  • DKFZp686F2182
  • Drosophila)
  • dunce-like phosphodiesterase E4
  • EC 3.1.4
  • EC
  • MGC126529
  • PDE32
  • phosphodiesterase 4B, cAMP-specific (dunce (Drosophila)-homologphosphodiesterase E4)
  • phosphodiesterase 4B, cAMP-specific (dunce
  • phosphodiesterase 4B, cAMP-specific
  • phosphodiesterase E4 dunce homolog


This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies


Isotype Controls

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Contact Information

Product PDFs


Gene Symbol PDE4B

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