P2X7/P2RX7 Antibody Blocking Peptide

• Reactivity: Hu
• Applications: AC
• Concentration: LYOPH

P2X7/P2RX7 Antibody Blocking Peptide Summary

• Description: A P2X7/P2RX7 antibody blocking peptide.
• Immunogen: YETNKVTRIQSMNY-C
• Protein/Peptide Type: Antibody Blocking Peptide
• Gene: P2RX7

Applications/Dilutions

• Dilutions:
  • Antibody Competition
• Application Notes: This peptide is useful as a blocking peptide for NBP1-37775.
  
  For further blocking peptide related protocol, click here.

Packaging, Storage & Formulations

• Storage: Store at -20C.
• Buffer: Lyophilised peptide, formulation 5pmol/uL in 5% (v/v) acetonitrile/H2O
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute pellet in distilled water where required. For Blocking studies, reconstitute pellet in 200ul distilled water to obtain a 0.5mg/ml peptide solution.

Alternate Names for P2X7/P2RX7 Antibody Blocking Peptide

• ATP receptor
• MGC20089
• P2RX7
• P2X purinoceptor 7
• P2X7
• P2X7P2X7 receptor
• P2X7R
• P2Z receptor
• purinergic receptor P2X, ligand-gated ion channel, 7
• purinergic receptor P2X7 variant A
• Purinergic receptor

Background

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants which would encode different isoforms have been identified although some fit nonsense-mediated decay (NMD) criteria. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: P2RX7