P2X1/P2RX1 Antibody (551820) [Alexa Fluor™ Plus 488]

• Clone: 551820
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 488

P2X1/P2RX1 Antibody (551820) [Alexa Fluor™ Plus 488] Summary

• Specificity: Detects human P2X1/P2RX1 in direct ELISAs.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Background

Biologic responses to ATP, ADP, and other extracellular nucleotides are mediated by P2-nucleotide receptors belonging to 2 major classes: G protein-coupled P2Y receptors and nucleotide-gated ion channel P2X receptors. P2RX1 functions as a ligand-gated ion channel with relatively high calcium permeability. Mouse studies suggest that this receptor is essential for normal male reproductive function. The development of selective antagonists for this receptor may provide an effective non-hormonal male contraceptive pill.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.