Species: Hu
Applications: Flow, CyTOF-ready
Host: Mouse Monoclonal
Species: Hu
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: ICC/IF
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ELISA, MA, AP
Description
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle, being responsible, for example, for sympathetic vasoconstriction in small arteries, arterioles and vas deferens. Mouse studies suggest that this receptor is essential for normal male reproductive function. It is possible that the development of selective antagonists for this receptor may provide an effective non-hormonal male contraceptive pill.
Bioinformatics
| Uniprot |
Human
Human
|
| Product By Gene ID |
5023 |
| Alternate Names |
- ATP receptor
- P2X purinoceptor 1
- P2X receptor, subunit 1
- P2X1P2X1 receptor
- purinergic receptor P2X, ligand-gated ion channel, 1
- Purinergic receptor
|
Research Areas for P2X1/P2RX1
Find related products by research area and learn more about each of the different research areas below.
Signal Transduction
![Flow Cytometry P2X1/P2RX1 Antibody (551820) [Unconjugated]](http://images.novusbio.com/fullsize/antibody/mab10533_human-p2x1-p2rx1-mab-clone-551820-flow-cytometry-562020175418.jpg)
