p18INK4c/CDKN2C Antibody (18P118 (DCS-118))

Images

 
Western Blot: p18INK4c/CDKN2C Antibody (18P118 (same as DCS-118)) [NB120-3216] - Analysis of HeLa Cells.
Immunohistochemistry-Paraffin: p18INK4c/CDKN2C Antibody (18P118 (same as DCS-118)) [NB120-3216] - Human tonsil stained with p18 (NB120-3216) using peroxidase-conjugate and AEC chromogen. Note nuclear staining of cells.
Immunoprecipitation: p18INK4c/CDKN2C Antibody (18P118 (same as DCS-118)) [NB120-3216] - Analysis of native IP.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, IHC, IHC-P, IP, ICC/IF
Clone
18P118 (DCS-118)
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
0.4 mg/ml

Order Details

p18INK4c/CDKN2C Antibody (18P118 (DCS-118)) Summary

Immunogen
Purified recombinant p18INK4c protein
Localization
Nuclear. Cytoplasmic.
Specificity
p18 (18P118 (same as DCS-118))
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
CDKN2C
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1 - 2 ug/ml
  • Immunohistochemistry 1:10 - 1:500
  • Immunohistochemistry-Paraffin 1:50
  • Immunoprecipitation 1 - 2 ug/ml
  • Immunofluorescence 1:10 - 1:500
Application Notes
WB: Detects an approx. 18 kDa, which corresponds to the predicted molecular weight of p18 / INK4c.
Theoretical MW
18 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Control
HeLa Whole Cell Lysate
Human Tonsil Whole Tissue Lysate (Adult Whole Normal)
p18INK4c/CDKN2C Overexpression Lysate
p18INK4c/CDKN2C Knockout HeLa Cell Lysate
Publications
Read Publications using
NB120-3216 in the following applications:

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS (pH 7.4) and 0.2% BSA
Preservative
0.09% Sodium Azide
Concentration
0.4 mg/ml
Purity
Protein G purified

Alternate Names for p18INK4c/CDKN2C Antibody (18P118 (DCS-118))

  • CDK6 inhibitor p18
  • CDKN2C
  • CDKN6
  • cyclin-dependent inhibitor
  • cyclin-dependent kinase 4 inhibitor C
  • Cyclin-dependent kinase 6 inhibitor
  • cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
  • INK4Ccyclin-dependent kinase 6 inhibitor p18
  • p18
  • p18INK4c
  • p18-INK4C
  • p18-INK6

Background

p18 INK4c is a specific inhibitor of cdk4 / cdk6 (interacts strongly with CDK6 and weakly with CDK4), and is expressed during G1 to S transition in the eukaryotic cell division cycle. It is maximally induced as cells enter S phase. Highest expression levels found in skeletal muscle. Also found in pancreas and heart.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for p18INK4c/CDKN2C Antibody (NB120-3216)(2)

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Control Lysate(s)

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Bioinformatics

Gene Symbol CDKN2C
Entrez
Uniprot