OSBP2 Antibody

Product Discontinued

OSBP2 Antibody Summary

• Immunogen: Peptide with sequence KEKQDWHMCPNIF corresponding to C-Terminus according to NP_110385.1.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: OSBP2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:32000
• Application Notes: WB: Preliminary experiments gave no signal but low background in human testis and brain extracts at up to 1 ug/ml.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris (pH 7.3), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Notes

Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.

Alternate Names for OSBP2 Antibody

• ORP4ORP-4KIAA1664Oxysterol-binding protein-related protein 4
• OSBPL1
• OSBPL4
• OSBP-related protein 4
• oxysterol binding protein 2
• oxysterol binding protein-like 1
• oxysterol binding protein-related protein 4
• oxysterol-binding protein 2

Background

Oxysterols are byproducts of cholesterol that can have cytotoxic effects on many cell types. The membrane-bound protein encoded by this gene contains a pleckstrin homology (PH) domain and an oxysterol-binding region. It binds oxysterols such as 7-ketocholesterol and may inhibit their cytotoxicity. Alternate transcriptional splice variants have been observed but have not been fully characterized. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for OSBP2 Antibody (NB100-1330)(1)

Publication using NB100-1330

• Moreira EF, Jaworski C, Li A, Rodriguez IR. Molecular and biochemical characterization of a novel oxysterol-binding protein (OSBP2) highly expressed in retina. J Biol Chem 2001-05-25 [PMID: 11278871]

Bioinformatics

• Gene Symbol: OSBP2
• Entrez:
  • 23762(Human)
  • 74309(Mouse)
• Uniprot:
  • NP_110385.(Human)