OBCAM/OPCML Antibody [mFluor Violet 450 SE]

• Reactivity: Hu
• Applications: WB, Flow, IHC, CyTOF-ready, ICC/IF
• Clonality: Polyclonal
• Host: Goat
• Conjugate: mFluor Violet 450 SE

OBCAM/OPCML Antibody [mFluor Violet 450 SE] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human OBCAM/OPCML
  Gly28-Asn322
  Accession # Q14982
• Specificity: Detects human OBCAM/OPCML in direct ELISAs and Western blots. In direct ELISAs, less than 5% cross-reactivity with recombinant human (rh) KILON is observed and less than 1% cross-reactivity with rhLAMP is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: OPCML
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Flow Cytometry
  • Immunocytochemistry
  • Immunohistochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for OBCAM/OPCML Antibody [mFluor Violet 450 SE]

• IgLON family member 1
• IGLON1opioid-binding protein/cell adhesion molecule-like
• OBCAM
• OBCAMopiate binding-cell adhesion molecule
• OPCM
• OPCML
• opioid binding protein/cell adhesion molecule-like preprotein
• opioid binding protein/cell adhesion molecule-like
• Opioid-binding cell adhesion molecule
• opioid-binding protein/cell adhesion molecule

Background

OPCML encodes a member of the IgLON subfamily in the immunoglobulin protein superfamily. The encoded protein is localized in the plasma membrane and may have an accessory role in opioid receptor function. This gene has an ortholog in rat and bovine. The opioid binding-cell adhesion molecule encoded by the rat gene binds opioid alkaloids in the presence of acidic lipids, exhibits selectivity for mu ligands and acts as a GPI-anchored protein. Since the encoded protein is highly conserved in species during evolution, it may have a fundamental role in mammalian systems. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: OPCML