OAS1 Antibody - Azide and BSA Free

Western Blot: OAS1 Antibody [H00004938-D03P] - Analysis of OAS1 expression in transfected 293T cell line by OAS1 polyclonal antibody.Lane 1: OAS1 transfected lysate(40.04 KDa).Lane 2: Non-transfected lysate.

Immunocytochemistry/Immunofluorescence: OAS1 Antibody [H00004938-D03P] - Analysis of antibody to OAS1 on HeLa cell. Antibody concentration 30 ug/ml.

• Reactivity: Hu
• Applications: WB, ICC/IF
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: Azide and BSA Free

OAS1 Antibody - Azide and BSA Free Summary

• Description: Quality control test: Antibody reactive against mammalian transfected lysate.
• Immunogen: OAS1 (AAH00562.1, 1 a.a. - 364 a.a.) full-length human protein. MMDLRNTPAKSLDKFIEDYLLPDTCFRMQINHAIDIICGFLKERCFRGSSYPVCVSKVVKGGSSGKGTTLRGRSDADLVVFLSPLTTFQDQLNRRGEFIQEIRRQLEACQRERAFSVKFEVQAPRWGNPRALSFVLSSLQLGEGVEFDVLPAFDALGQLTGSYKPNPQIYVKLIEECTDLQKEGEFSTCFTELQRDFLKQRPTKLKSLIRLVKHWYQNCKKKLGKLPPQYALELLTVYAWERGSMKTHFNTAQGFRTVLELVINYQQLCIYWTKYYDFKNPIIEKYLRRQLTKPRPVILDPADPTGNLGGGDPKGWRQLAQEAEAWLNYPCFKNWDGSPVSSWILLVRPPASSLPFIPAPLHEA
• Specificity: 2',5'-oligoadenylate synthetase 1, 40/46kDa
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: OAS1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:10-1:500
  • Western Blot 1:100-1:2000
• Application Notes: This antibody is reactive against mammalian transfected lysate in WB. It has been used for ELISA.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for OAS1 Antibody - Azide and BSA Free

• (2-5')oligo(A) synthase 1,2'-5'-oligoadenylate synthetase 1,2-5A synthase 1,2'-5'-oligoisoadenylate synthetase 1
• (2-5')oligo(A) synthetase 1
• 2'-5'-oligo A synthetase 1
• 2'-5'-oligoadenylate synthase 1
• 2'-5'-oligoadenylate synthetase 1 (40-46 kD)
• 2'-5'-oligoadenylate synthetase 1, 40/46kDa
• E18/E16,2-5A synthetase 1
• EC 2.7.7
• EC 2.7.7.-
• IFI-4,2'-5' oligoadenylate synthetase 1 p52 isoform
• OIAS2'-5' oligoadenylate synthetase 1 p48 isoform
• OIASI
• p46/p42 OAS

Background

This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Mutations in this gene have been associated with host susceptibility to viral infection. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: OAS1
• Entrez:
  • 4938(Human)
• Uniprot:
  • AAH00562.1(Human)