Recombinant Human NSP 5 alpha 3 alpha His Protein

SDS-Page: NSP 5 alpha 3 alpha Recombinant Protein [NBP2-51745] - 15% SDS Page (3 ug)

• Reactivity: Hu
• Applications: PAGE
• Concentration: 0.25 mg/ml

Recombinant Human NSP 5 alpha 3 alpha His Protein Summary

• Description: A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 458-761 of Human NSP 5 alpha 3 alpha
  
  

  Source: E.coli

  Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSTQEGKII ELEQKCTGIL EQGRFEREKL LNIQQQLTCS LRKVEEENQG ALEMIKRLKE ENEKLNEFLE LERHNNNMMA KTLEECRVTL EGLKMENGSL KSHLQGEKQK ATEASAVEQT AESCEVQEML KVARAEKDLL ELSCNELRQE LLKANGEIKH VSSLLAKVEK DYSYLKEICD HQAEQLSRTS LKLQEKASES DAEIKDMKET IFELEDQVEQ HRAVKLHNNQ LISELESSVI KLEEQKSDLE RQLKTLTKQM KEETEEWRRF QADLQTAVVV ANDIKCEAQQ ELRTVKRKLL EEEEKNA

• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: SPECC1
• Purity: >80%, by SDS-PAGE

Applications/Dilutions

• Dilutions:
  • SDS-Page
• Theoretical MW: 37.7 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20 mM Tris-HCl buffer (pH8.0), 10% glycerol, 1 mM DTT, 0.1 M NaCl
• Preservative: No Preservative
• Concentration: 0.25 mg/ml
• Purity: >80%, by SDS-PAGE

Alternate Names for Recombinant Human NSP 5 alpha 3 alpha His Protein

• cytospin-B
• CYTSBcytospin B
• FLJ36955
• HCMOGT-1
• NSP
• NSP5
• Nuclear structure protein 5
• sperm antigen HCMOGT 1
• Sperm antigen HCMOGT-1
• sperm antigen with calponin homology and coiled coil domains 1
• sperm antigen with calponin homology and coiled-coil domains 1cytokinesis and spindle organization B
• sperm antigen with calponin-like and coiled coil domains 1
• structure protein NSP5a3a
• structure protein NSP5a3b
• structure protein NSP5b3a
• structure protein NSP5b3b

Background

NSP 5alpha 3alpha is a novel structure protein with potential roles in ribosome biogenesis and rRNA metabolism/processing. NSP5a3a is highly expressed in certain tumor cell lines, and may serve as a good tumor marker. In these cancer lines, NSP5a3a has been shown to interact with the nucleolar apoptosis protein B23 and may be involved in a novel p73 dependent apoptosis mechanism. Therefore, NSP5a3a is expected to become an important potential target for future cancer treatment research.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: SPECC1