Nicotinic Acetylcholine Receptor epsilon Antibody

Product Discontinued

Nicotinic Acetylcholine Receptor epsilon Antibody Summary

• Immunogen: CHRNE (NP_000071, 21 a.a. ~ 131 a.a) partial recombinant protein with GST tag.KNEELRLYHHLFNNYDPGSRPVREPEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSELVWLPEIVLENNIDGQFGVAYDANVLV
• Specificity: CHRNE - cholinergic receptor, nicotinic, epsilon polypeptide
• Clonality: Polyclonal
• Host: Mouse
• Gene: CHRNE
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot 1:500
• Application Notes: The quality control of this antibody is limited to Western blot on the immunizing protein. It has also been used for ELISA. Abnova's recommended working dilutions for western analysis are as follows: 1:500 dilution for ascites 1:1000 for purified Ig 1:500

Reactivity Notes

Human. Other species not tested.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: Unpurified antisera so the specific antibody concentration is unknown. Contains 50% glycerol.
• Preservative: No Preservative
• Purity: Unpurified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Nicotinic Acetylcholine Receptor epsilon Antibody

• acetylcholine receptor subunit epsilon
• AchR epsilon subunit
• ACHRE
• ACHREFCCMS
• cholinergic receptor, nicotinic, epsilon polypeptide
• cholinergic receptor, nicotinic, epsilon
• CHRNE
• CMS1D
• CMS1E
• CMS2A
• nAChR epsilon
• Nicotinic Acetylcholine R epsilon
• SCCMS

Background

Acetylcholine receptors at mature mammalian neuromuscular junctions are pentameric protein complexes composed of four subunits in the ratio of two alpha subunits to one beta, one epsilon, and one delta subunit. The achetylcholine receptor changes subunit composition shortly after birth when the epsilon subunit replaces the gamma subunit seen in embryonic receptors. Mutations in the epsilon subunit are associated with congenital myasthenic syndrome.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

FAQs for Nicotinic Acetylcholine Receptor epsilon Antibody (H00001145-A01). (Showing 1 - 1 of 1 FAQ).

1. I am looking to buy antibodies against most of the nicotinic receptor subunits for WB and IHC application. Could you please indicate which of your antibodies have been used by other researchers and provide publications showing their use? Thanks.
   • A list of our antibodies directed against he nicotinic acetylcholine receptors can be found here. Any products with publications will be indicated on the search page and can be found under the publications tab on the individual product's datasheet. Furthermore, we guarantee all of our products for the applications and species list on the datasheet. This should help narrow down your search.

Bioinformatics

• Gene Symbol: CHRNE
• Entrez:
  • 1145(Human)
• OMIM:
  • 100725(Human)
• Uniprot:
  • NP_000071()