Neuromedin BR/NMBR Antibody (466505) [Alexa Fluor® 350]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
466505
Clonality
Monoclonal
Host
Mouse
Conjugate
Alexa Fluor 350
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.

Order Details

Neuromedin BR/NMBR Antibody (466505) [Alexa Fluor® 350] Summary

Immunogen
NS0 mouse myeloma cell line transfected with human NMBR
Met1-Met390
Accession # AAB27330
Specificity
Detects human Neuromedin B R/NMBR. Stains human Neuromedin B R/NMBR transfectants but not irrelevant transfectants.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
NMBR
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Intracellular Staining by Flow Cytometry 0.25-1 ug/10^6 cells
Application Notes
Flow Cytometry: Please use 0.25-1 ug of conjugated antibody per 10e6 cells.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Buffer
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Preservative
0.09% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Neuromedin BR/NMBR Antibody (466505) [Alexa Fluor® 350]

  • Neuromedin B R
  • neuromedin B receptor
  • Neuromedin BR
  • neuromedin-B receptor
  • Neuromedin-B-preferring bombesin receptor
  • NMBR
  • NMB-R

Background

Neuromedin B Receptor (NMBR) is an 80 kDa, 390 amino acid (aa) G-protein coupled 7-transmembrane glycoprotein receptor for bombesin-like peptides, binding Neuromedin B with high affinity and GRP (gastrin releasing peptide) with lower affinity.  Neuromedin B R expression in the olfactory and central thalamic regions of the brain plays a role in thermoregulation. It has also been shown to be mitogenic in colonic epithelium. Expression in the pituitary gland is important for regulation of the pituitary-thyroid axis. Within extracellular domains, human Neuromedin B R shares 86% and 82% aa identity with mouse and rat Neuromedin B R, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs for Neuromedin BR/NMBR Antibody (IC4728U) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 IC4728U
Alexa Fluor 405 IC4728V
Alexa Fluor 488 IC4728G
Alexa Fluor 532 FAB4728X
Alexa Fluor 594 IC4728T
Alexa Fluor 647 IC4728R
Alexa Fluor 700 IC4728N
Alexa Fluor 750 IC4728S
Allophycocyanin FAB4728A
Biotin FAB4728B
DyLight 350 FAB4728D
DyLight 405 FAB4728E
DyLight 488 FAB4728K
DyLight 550 FAB4728L
DyLight 594 FAB4728M
DyLight 650 FAB4728W
DyLight 680 FAB4728Y
DyLight 755 FAB4728Z
FITC FAB4728F
Janelia Fluor 549 FAB4728I
Janelia Fluor 646 FAB4728J
PE FAB4728P
PerCP FAB4728C

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Bioinformatics Tool for Neuromedin BR/NMBR Antibody (IC4728U)

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Bioinformatics

Gene Symbol NMBR
Uniprot