Neurexin 1 beta/NXRN1b Antibody [Alexa Fluor™ Plus 555]

• Reactivity: Rt
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: Alexa Fluor Plus 555

Neurexin 1 beta/NXRN1b Antibody [Alexa Fluor™ Plus 555] Summary

• Specificity: Detects rat Neurexin 1 beta /NXRN1b in direct ELISAs and Western blots. In direct ELISAs, approximately 25% cross‑reactivity with recombinant rat Neurexin 1 alpha is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Neurexin 1 beta/NXRN1b Antibody [Alexa Fluor™ Plus 555]

• Hs.22998
• Neurexin 1 beta
• NXR1B
• NXRN1b
• PTHSL2
• SCZD17

Background

Neurexin 1 beta is an 80 kDa member of the Neurexin family of proteins. It is expressed on neuronal presynaptic membranes and contributes to synapse formation through binding to postsynaptic neuroligins. An alternate start site in the Neurexin 1 gene generate an alpha - (long) and beta - (short) isoform. Mature rat Neurexin 1 beta is a type I transmembrane glycoprotein that is 468 amino acids (aa) in length. It has a 346 aa extracellular region (aa 47‑392) that contains one laminin-like G domain (aa 91‑264). Within the G domain, the presence or absence of a splice site (aa 201‑230) materially impacts neuroligin binding. Over aa 47‑392, rat Neurexin 1 beta is 100% and 98% aa identical to mouse and human Neurexin 1 beta , respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.