Neprilysin-2/MMEL1 Antibody (353207) [DyLight 680]

• Reactivity: Hu
• Applications: WB, IP
• Clone: 353207
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 680

Neprilysin-2/MMEL1 Antibody (353207) [DyLight 680] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human Neprilysin-2
  Gly78-Trp779
  Accession # Q495T6
• Specificity: Detects human Neprilysin‑2/MMEL1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) Neprilysin, rhECE‑1 or rhECE‑2 is observed.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: MMEL1
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Neprilysin-2/MMEL1 Antibody (353207) [DyLight 680]

• EC 3.4.24
• EC 3.4.24.11
• MELL1
• membrane metallo-endopeptidase-like 1
• Membrane metallo-endopeptidase-like 2MGC119455
• MGC119454
• MMEL1
• MMEL2
• NEP2
• NEP2(m)
• NEPIIMGC119456
• Neprilysin II
• Neprilysin2
• Neprilysin-2
• NL2
• NL2NL1
• SEP
• soluble secreted endopeptidase
• zinc metallopeptidase

Background

MMELL1 is encoded by this gene is a member of the neutral endopeptidase (NEP) or membrane metallo-endopeptidase (MME) family. Family members play important roles in pain perception, arterial pressure regulation, phosphate metabolism and homeostasis. This protein is a type II transmembrane protein and is thought to be expressed as a secreted protein. This gene is expressed mainly in testis with weak expression in the brain, kidney, and heart. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MMEL1