NAALADase-like 2/NAALADL2 Antibody (817227) [Alexa Fluor® 594]

• Reactivity: Hu
• Applications: IHC
• Clone: 817227
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 594

NAALADase-like 2/NAALADL2 Antibody (817227) [Alexa Fluor® 594] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human NAALADase‑like 2/NAALADL2
  Ser152-Asn795
  Accession # Q58DX5
• Specificity: Detects human NAALADase‑like 2/NAALADL2 in ELISAs.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for NAALADase-like 2/NAALADL2 Antibody (817227) [Alexa Fluor® 594]

• inactive N-acetylated-alpha-linked acidic dipeptidase-like protein 2
• NAALADase L2
• NAALADase like 2
• NAALADase-like 2
• NAALADL2
• N-acetylated alpha-linked acidic dipeptidase 2
• N-acetylated alpha-linked acidic dipeptidase-like 2

Background

NAALADL2 (N-acetylated alpha -linked acidic dipeptidase like 2) is a member of the peptidase M28 family of enzymes. It is presumably a type II transmembrane (TM) protein that may have O-glycosyl hydrolase activity. Human NAALADL2 is 795 amino acids (aa) in length. It is believed to contain a cytoplasmic and TM segment at the N-terminus, followed by a peptidase domain (aa 444‑596) and a TfR-like dimerization region (aa 688‑777). There are multiple splice forms. One shows a 4 aa substitution for aa 292‑795, a second shows an alternate start site at Met18 with a 24 aa substitution for aa 314‑795, and a third contains an alternate start site at Met283, accompanied by a deletion of aa 363‑411 and 633‑795. Over aa 152‑795, human NAALADL2 shares 87% and 82% aa sequence identity with mouse and canine NAALADL2, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.