Muscarinic Acetylcholine Receptor M2/CHRM2 Antibody (585713) [Alexa Fluor™ Plus 555]

• Reactivity: Hu
• Clone: 585713
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 555

Muscarinic Acetylcholine Receptor M2/CHRM2 Antibody (585713) [Alexa Fluor™ Plus 555] Summary

• Specificity: Detects human CHRM2 in immunohistochemistry.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Muscarinic Acetylcholine Receptor M2/CHRM2 Antibody (585713) [Alexa Fluor™ Plus 555]

• 7TM receptor
• cholinergic receptor, muscarinic 2
• CHRM2
• FLJ43243
• HM2
• mAChR M2
• MGC120006
• MGC120007
• muscarinic acetylcholine receptor M2
• muscarinic M2 receptor

Background

Muscarinic acetylcholine receptor M2 (CHRM2) is a 60 kDa 7-transmembrane glycoprotein that is predominantly expressed in the heart and central nervous system. CHRM2 mediates signal transduction in the autonomic nervous system in response to muscarinic agonists. Polymorphisms of CHRM2 are associated with alcohol dependence, depression, bipolar disorder, and recovery of heart function after myocardial infarction. Human CHRM2 shares 96% aa sequence identity with mouse and rat CHRM2.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.