MSP/MST1 Antibody (45904) [Alexa Fluor™ Plus 680]

• Reactivity: Hu
• Clone: 45904
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 680

MSP/MST1 Antibody (45904) [Alexa Fluor™ Plus 680] Summary

• Specificity: Detects human MSP alpha Chain in ELISAs and Western blots. In Western blots, no cross-reactivity with recombinant human (rh) HGF or rhIL‑6 is observed.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for MSP/MST1 Antibody (45904) [Alexa Fluor™ Plus 680]

• D3F15S2
• EC 3.4.21
• hepatocyte growth factor-like protein homolog
• HGFL
• HGFLhepatocyte growth factor-like protein
• macrophage stimulating 1 (hepatocyte growth factor-like)
• Macrophage stimulatory protein
• Macrophage-stimulating protein
• MSP
• MSPDNF15S2
• MST1
• NF15S2
• SF2

Background

MSP, also known as hepatocyte growth factor-like protein (HGFl), and scatter factor-2 (SF2), is a member of the HGF family of growth factors. It is secreted as a single chain inactive precursor which is proteolytically activated to yield a biologically active disulfide-linked heterodimer of the alpha and beta chains. MSP induces keratinocyte proliferation, bone resorption, and cell migration and shape change in resident macrophages. Heterodimeric MSP binds to and activates the cell surface receptor tyrosine kinase, RON/STK, which is expressed on mature macrophages, keratinocytes, and vascular endothelium of wounded skin.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.