MS4A4B Antibody (444008) [Alexa Fluor™ Plus 594]

• Reactivity: Mu
• Clone: 444008
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Alexa Fluor Plus 594

MS4A4B Antibody (444008) [Alexa Fluor™ Plus 594] Summary

• Specificity: Detects mouse MS4A4B. Stains mouse MS4A4B transfectants but not irrelevant transfectants.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for MS4A4B Antibody (444008) [Alexa Fluor™ Plus 594]

• AI463180
• Chandra
• Ly116
• MS4A4B

Background

MS4A4B, also called Chandra, is a member of the MS4A family of four-transmembrane proteins that includes CD20. It is expressed in immature CD4^-CD8^- T cells, and later in mature Th1 but not Th2 cells. MS4A4B is enriched in lipid rafts of activated T cells, and overexpression enhances Th1 cytokine expression, indicating a possible role in cell signaling. Mouse MS4A4B shares 69% overall amino acid (aa) identity with rat, and low (< 40%) aa identity with human MS4A4B.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.