MS4A4B Products


Description

MS4A4B, also called Chandra, is a member of the MS4A family of four-transmembrane proteins that includes CD20. It is expressed in immature CD4-CD8- T cells, and later in mature Th1 but not Th2 cells. MS4A4B is enriched in lipid rafts of activated T cells, and overexpression enhances Th1 cytokine expression, indicating a possible role in cell signaling. Mouse MS4A4B shares 69% overall amino acid (aa) identity with rat, and low (< 40%) aa identity with human MS4A4B.



Bioinformatics

Uniprot
Product By Gene ID 60361
Alternate Names
  • AI463180
  • Chandra
  • Ly116
  • MS4A4B