MMACHC Antibody

Western Blot: MMACHC Antibody [H00025974-B01P] - Analysis of MMACHC expression in transfected 293T cell line by MMACHC polyclonal antibody. Lane 1: MMACHC transfected lysate(24.75 KDa). Lane 2: Non-transfected lysate.

Product Discontinued

MMACHC Antibody Summary

• Immunogen: MMACHC (AAH06122.3, 1 a.a. - 225 a.a.) full-length human protein. MFDRALKPFLQSCHLRMLTDPVDQCVAYHLGRVRESLPELQIEIIADYEVHPNRRPKILAQTAAHVAGAAYYYQRQDVEADPWGNQRISGVCIHPRFGGWFAIRGVVLLPGIEVPDLPPRKPHDCVPTRADRIALLEGFNFHWRDWTYRDAVTPQERYSEEQKAYFSTPPAQRLALLGLAQPSEKPSSPSPDLPFTTPAPKKPGNPSRARSWLSPRVSPPASPGP
• Specificity: MMACHC - methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria,
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: MMACHC
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500
• Application Notes: Antibody reactive against Recombinant Protein with GST tag on ELISA and Western Blot and also on transfected lysate in western blot. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for MMACHC Antibody

• cblC
• DKFZP564I122
• FLJ25671
• methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
• methylmalonic aciduria and homocystinuria type C protein
• RP11-291L19.3

Background

The exact function of the protein encoded by this gene is not known, however, its C-terminal region shows similarity to TonB, a bacterial protein involved in energy transduction for cobalamin (vitamin B12) uptake. Hence, it is postulated that this protein may have a role in the binding and intracellular trafficking of cobalamin. Mutations in this gene are associated with methylmalonic aciduria and homocystinuria type cblC. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MMACHC
• Entrez:
  • 25974(Human)
• Uniprot:
  • AAH06122.3(Human)