MKRN1 Antibody (OTI2C8) [mFluor Violet 610 SE]

MKRN1 Antibody (OTI2C8) [mFluor Violet 610 SE] [NBP2-72718MFV610] - Vial of mFluor Violet 610 conjugated antibody. mFluor Violet 610 is optimally excited at 421 nm by the Violet laser (405 nm) and has an emission maximum of 613 nm.

• Reactivity: Hu, Mu
• Applications: WB, Flow, IHC
• Clone: OTI2C8
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: mFluor Violet 610 SE

MKRN1 Antibody (OTI2C8) [mFluor Violet 610 SE] Summary

• Immunogen: Full length human recomnbinant protein of human MKRN1(NP_038474) produced in HEK293T cell.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: MKRN1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for MKRN1 Antibody (OTI2C8) [mFluor Violet 610 SE]

• E3 ubiquitin-protein ligase makorin-1
• EC 6.3.2.-
• FLJ21334
• makorin ring finger protein 1
• RNF61RING finger protein 61

Background

MKRN1 was identified as a repressor of c-Jun, androgen receptor, and retinoic acid receptor transcriptional activity. MKRN1 is a RING zinc finger protein that has been demonstrated to function as an E3 ubiquitin ligase. The repressive activity of MKRN1 is not dependent on its ubiquitin ligase activity. MKRN1 also appears to function as a transactivator of RNA polymerase II dependent transcription.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MKRN1