Melatonin Receptor 1B Antibody [HRP]


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Product Details

Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IHC, IHC-P

Melatonin Receptor 1B Antibody [HRP] Summary

A synthetic peptide made to an internal region of the human Melatonin Receptor 1B protein (within residues 200-300) [Swiss-Prot P49286].
Cell membrane; Multi-pass membrane protein.
Immunogen affinity purified
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  • Western Blot 1:1000
  • Immunohistochemistry 1:100
  • Immunohistochemistry-Paraffin 1:100
Application Notes
This Melatonin Receptor 1B antibody is useful for Immunohistochemistry with formalin fixed paraffin embedded tissues and Western blot. Prior to immunostaining paraffin tissues, antigen retrieval with sodium citrate buffer (pH 6.0) is recommended. Use in Immunohistochemistry-Frozen reported in scientific literature (PMID 24365461)
Readout System

Reactivity Notes

Human, mouse and rat

Packaging, Storage & Formulations

Store at 4C in the dark.
No Preservative
Immunogen affinity purified

Alternate Names for Melatonin Receptor 1B Antibody [HRP]

  • FGQTL2
  • Mel 1b melatonin receptor
  • Mel1b receptor
  • MEL-1B-R
  • melatonin receptor 1B
  • melatonin receptor MEL1B
  • melatonin receptor type 1B
  • MT2


Melatonin receptor type 1B (MTNR1B) is a member of the G-protein coupled receptor 1 family. This family is responsible for translating external chemical signals across the cell membrane. MTNR1B is one of two high affinity receptors for melatonin, a hormone secreted by the pineal gland. Pertussis toxin sensitive G proteins, that inhibit adenylate cyclase activity, control the MTNR1B receptor. MTNR1B is expressed in the retina, and to a lesser extent the brain and hippocampus. MTNR1B is thought to regulate reproduction, the circadian cycle, and neurological melatonin levels; as well as participate in light dependent function in the retina. Post translational modifications that may affect MTNR1B are disulfide bonds and glycosylation.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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WB Video Protocol

FAQs for Melatonin Receptor 1B Antibody (NLS932H). (Showing 1 - 1 of 1 FAQ).

  1. I saw that you have the antibodies for the both receptors of melatonin but not listed with FACS application. I need more information about what is better for my assay.
    • At this time, none of our melatonin receptor antibodies have been tested and validated in Flow. Should you choose to purchase and test one of them, you would qualify for the Innovator's Rewards program. You should take a look at each individual antibody, the clonality, conjugates, immunogen region and all relevant data in order to decide which product would be most suitable for your needs.

Secondary Antibodies


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Gene Symbol MTNR1B