MEL-18 Antibody

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

MEL-18 Antibody Summary

Immunogen
This antibody was made against a protein fragment from the Middle Region
Specificity
This product is specific for Human PCGF2.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PCGF2
Purity
Immunogen affinity purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:5000-1:20000
  • ELISA 1:100-1:2000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:250-1:2000
Application Notes
This antibody is useful in ELISA, Western Blot and Immunohistochemistry-Paraffin.
Publications
Read Publications using 21650002.

Reactivity Notes

Human.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20mM Potassium Phosphate (pH 7.0) and 0.15M NaCl
Preservative
No Preservative
Purity
Immunogen affinity purified

Notes

Manufactured by SDIX's proprietary Genomic Antibody Technology™. GAT FAQs. These products are available in limited quantities. Please enquire about the availability of this product before purchasing.

Alternate Names for MEL-18 Antibody

  • MEL-18
  • polycomb group ring finger 2
  • polycomb group RING finger protein 2
  • RING finger protein 110DNA-binding protein Mel-18
  • RNF110MEL18
  • Zinc finger protein 144
  • ZNF144MGC10545

Background

The protein encoded by this gene contains a RING finger motif and is similar to the polycomb group (PcG) gene products. PcG gene products form complexes via protein-protein interaction and maintain the transcription repression of genes involved in embryogenesis, cell cycles, and tumorigenesis. This protein was shown to act as a negative regulator of transcription and has tumor suppressor activity. The expression of this gene was detected in various tumor cells, but is limited in neural organs in normal tissues. Knockout studies in mice suggested that this protein may negatively regulate the expression of different cytokines, chemokines, and chemokine receptors, and thus plays an important role in lymphocyte differentiation and migration, as well as in immune responses.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for MEL-18 Antibody (21650002)(2)

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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for MEL-18 Antibody (21650002) (0)

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol PCGF2
Uniprot