Species: Hu, Bv, Ca
Applications: WB, ELISA
Host: Goat Polyclonal
Species: Hu
Applications: WB, ELISA
Host: Mouse Monoclonal
Species: Hu, Mu, Rt
Applications: ICC/IF
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
MEL-18 is a transcriptional repressor that binds specifically to the DNA sequence 5'-GACTNGACT-3'. Mel18 has tumor suppressor activity and may play a role in cell proliferation and/or neural cell development. It regulates proliferation of early T progenitor cells by maintaining expression of HES1. Also plays a role in antero-posterior specification of the axial skeleton and negative regulation of the self-renewal activity of hematopoietic stem cells.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
Human
Human
|
| Product By Gene ID |
7703 |
| Alternate Names |
- MEL-18
- polycomb group ring finger 2
- polycomb group RING finger protein 2
- RING finger protein 110DNA-binding protein Mel-18
- RNF110MEL18
- Zinc finger protein 144
- ZNF144MGC10545
|
Research Areas for MEL-18
Find related products by research area and learn more about each of the different research areas below.
Zinc Finger
