MAPKAP Kinase 3 Antibody (4B11)

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Western Blot: MAPKAP Kinase 3 Antibody (4B11) [H00007867-M06] - Analysis of MAPKAPK3 expression in HL-60 (Cat # L014V1).

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clone
4B11
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

MAPKAP Kinase 3 Antibody (4B11) Summary

Immunogen
MAPKAPK3 (NP_004626, 59 a.a. - 153 a.a.) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. LECFHRRTGQKCALKLLYDSPKARQEVDHHWQASGGPHIVCILDVYENMHHGKRCLLIIMECMEGGELFSRIQERGDQAFTEREAAEIMRDIGTA
Specificity
MAPKAPK3 (4B11)
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Mouse
Gene
MAPKAPK3
Purity
IgG purified
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Applications/Dilutions

Dilutions
  • Western Blot
  • ELISA
Application Notes
Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for ELISA.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
IgG purified

Notes

Quality control test: Antibody Reactive Against Recombinant Protein.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for MAPKAP Kinase 3 Antibody (4B11)

  • 3PKEC 2.7.11.1
  • Chromosome 3p kinase
  • EC 2.7.11
  • MAP kinase-activated protein kinase 3
  • MAPK-activated protein kinase 3
  • MAPKAP kinase 3
  • MAPKAP33pK
  • MAPKAPK-3
  • mitogen-activated protein kinase-activated protein kinase 3

Background

This gene encodes a member of the Ser/Thr protein kinase family. This kinase functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This kinase was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. This kinase was reported to interact with, phosphorylate and repress the activity of E47, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and cell differentiation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol MAPKAPK3
Entrez
OMIM
Uniprot