MACF1 Antibody

Western Blot: MACF1 Antibody [H00023499-A01] - Detection against Immunogen (36.45 KDa) .

Product Discontinued

MACF1 Antibody Summary

• Immunogen: MACF1 (AAH07330, 1 a.a. - 95 a.a.) partial recombinant protein with GST tag. KIEDEVTRQVAQCKCAKRFQVEQIGENKYRFGDSQQLRLVRILRSTVMVRVGGGWMALDEFLVKNDPCRARGRTNIELREKFILPEGASQGMTPF
• Specificity: MACF1 - microtubule-actin crosslinking factor 1
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: MACF1
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Western Blot 1:500
• Application Notes: The quality control of this antibody is limited to Western blot on the immunizing protein.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 50% Glycerol
• Preservative: No Preservative
• Purity: Unpurified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for MACF1 Antibody

• microtubule-actin crosslinking factor 1

Background

The protein encoded by this gene belongs to the plakin family of cytoskeletal linker proteins. This protein family forms bridges between different cytoskeletal elements through specialized modular domains. The encoded protein is one of the largest size proteins identified in human cytoskeletal proteins. It has functional actin and microtubule binding domains, and it appears to stabilize actin at sites where microtubules and microfilaments meet. It may function in microtubule dynamics to facilitate actin-microtubule interactions at the cell periphery and to couple the microtubule network to cellular junctions. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for MACF1 Antibody (H00023499-A01)(2)

Publications using H00023499-A01

• Jorgensen LH, Mosbech MB, Faergeman NJ et al. Duplication in the microtubule-actin cross-linking factor 1 gene causes a novel neuromuscular condition. Sci Rep. 2014-01-01 [PMID: 24899269] (WB)
• Khositseth S, Pisitkun T, Slentz DH et al. Quantitative protein and mRNA profiling shows selective post-transcriptional control of protein expression by vasopressin in kidney cells. Mol. Cell Proteomics. 10(1):M110.004036. 2011-01-01 [PMID: 20940332]

Bioinformatics

• Gene Symbol: MACF1
• Entrez:
  • 23499(Human)
• OMIM:
  • 608271(Human)
• Uniprot:
  • AAH07330(Human)