Lyp/PTPN22 Antibody

Western Blot: Lyp/PTPN22 Antibody [H00026191-B01P] - Analysis of PTPN22 expression in transfected 293T cell line by PTPN22 polyclonal antibody. Lane1:PTPN22 transfected lysate(82.72 KDa). Lane2:Non-transfected lysate.

Product Discontinued

Lyp/PTPN22 Antibody Summary

• Immunogen: PTPN22 (AAH71670.1, 1 a.a. - 752 a.a.) full-length human protein. MDQREILQKFLDEAQSKKITKEEFANEFLKLKRQSTKYKADKTYPTTVAEKPKNIKKNRYKDILPYDYSRVELSLITSDEDSSYINANFIKGVYGPKAYIATQGPLSTTLLDFWRMIWEYSVLIIVMACMEYEMGKKKCERYWAEPGEMQLEFGPFSVSCEAEKRKSDYIIRTLKVKFNSETRTIYQFHYKNWPDHDVPSSIDPILELIWDVRCYQEDDSVPICIHCSAGCGRTGVICAIDYTWMLLKDGSQAKHCIPEKNHTLQADSYSPNLPKSTTKAAKMMNQQRTKMEIKESSSFDFRTSEISAKEELVLHPAKSSTSFDFLELNYSFDKNADTTMKWQTKAFPIVGEPLQKHQSLDLGSLLFEGCSNSKPVNAAGRYFNSKVPITRTKSTPFELIQQRETKEVDSKENFSYLESQPHDSCFVEMQAQKVMHVSSAELNYSLPYDSKHQIRNASNVKHHDSSALGVYSYIPLVENPYFSSWPPSGTSSKMSLDLPEKQDGTVFPSSLLPTSSTSLFSYYNSHDSLSLNSPTNISSLLNQESAVLATAPRIDDEIPPPLPVRTPESFIVVEEAGEFSPNVPKSLSSAVKVKIGTSLEWGGTSEPKKFDDSVILRPSKSVKLRSPKSELHQDRSSPPPPLPERTLESFFLADEDCMQAQSIETYSTSYPDTMENSTSSKQTLKTPGKSFTRSKSLKILRNMKKSICNSCPPNKPAESVQSNNSSSFLNFGFANRFSKPKGPRNPPPTWNI
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: PTPN22
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: This antibody is useful for Western Blot, Functional

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein G purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Lyp/PTPN22 Antibody

• EC 3.1.3.48
• Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP
• Lymphoid phosphatase
• lymphoid-specific protein tyrosine phosphatase
• Lyp
• Lyp1
• Lyp2
• LyPTP
• PEP
• PEST-domain phosphatase
• protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
• protein tyrosine phosphatase, non-receptor type 8
• PTPN22
• PTPN8 (former)
• PTPN8LYP1
• tyrosine-protein phosphatase non-receptor type 22

Background

PTPN22 encodes a protein tyrosine phosphatase which is expressed primarily in lymphoid tissues. This enzyme associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Alternative splicing of this gene results in two transcript variants encoding distinct isoforms.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PTPN22
• Uniprot:
  • AAH71670.1(Human)