Recombinant Human LSM4 Protein

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SDS-Page: Recombinant Human LSM4 Protein [NBP1-50944] - 15 % SDS-PAGE (3ug)

Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE
Concentration
0.5 mg/ml

Order Details

Recombinant Human LSM4 Protein Summary

Description
A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-139 of Human LSM4

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MLPLSLLKTA QNHPMLVELK NGETYNGHLV SCDNWMNINL REVICTSRDG DKFWRMPECY IRGSTIKYLR IPDEIIDMVK EEVVAKGRGR GGLQQQKQQK GRGMGGAGRG VFGGRGRGGI PGTGRGQPEK KPGRQAGKQ

Source
E. coli
Protein/Peptide Type
Recombinant Protein
Gene
LSM4
Purity
>90%, by SDS-PAGE

Applications/Dilutions

Theoretical MW
17.5 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT
Preservative
No Preservative
Concentration
0.5 mg/ml
Purity
>90%, by SDS-PAGE

Alternate Names for Recombinant Human LSM4 Protein

  • Glycine-rich protein
  • GRP
  • LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
  • U6 snRNA-associated Sm-like protein LSm4
  • YER112W

Background

LSM4, also called U6 snRNA-associated Sm-like protein or glycine-rich protein (GRP), forms donut-shaped heptameric complexes that are involved in various steps of RNA metabolism. It facilitates RNA protein interactions and structural changes that are required during ribosomal subunit assembly. It binds specifically to the 3'-terminal U-tract of U6 snRNA. Recombinant human LSM4 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol LSM4