LIR-8/CD85c/LILRB5 Antibody - BSA Free

Western Blot: LIR-8/CD85c/LILRB5 Antibody [NBP2-19352] - Sample (30 ug of whole cell lysate) A: K562 7. 5% SDS PAGE gel, diluted at 1:1000.

Immunohistochemistry-Paraffin: LIR-8/CD85c/LILRB5 Antibody [NBP2-19352] - Human breast carcinoma. LILRB5 antibody [N2C1], Internal dilution: 1:250. Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min.

• Reactivity: Hu, Pm
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

LIR-8/CD85c/LILRB5 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit LIR-8/CD85c/LILRB5 Antibody - BSA Free (NBP2-19352) is a polyclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Recombinant protein encompassing a sequence within the center region of human LIR-8/CD85c/LILRB5. The exact sequence is proprietary.
• Localization: Membrane; Single-pass type I membrane protein
• Predicted Species: Chimpanzee (94%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: LILRB5
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
  • Western Blot 1:500-1:3000
• Theoretical MW: 64 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 0.1M Tris, 0.1M Glycine, 10% Glycerol
• Preservative: 0.01% Thimerosal
• Purity: Antigen Affinity-purified

Alternate Names for LIR-8/CD85c/LILRB5 Antibody - BSA Free

• CD85 antigen-like family member C
• CD85c antigen
• CD85c
• Leukocyte immunoglobulin-like receptor 8
• leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains)
• LILRB5
• LIR8
• LIR-8
• LIR8CD85C
• LIR-8leukocyte immunoglobulin-like receptor subfamily B member 5
• member 5

Background

This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Bioinformatics

• Gene Symbol: LILRB5
• Uniprot:
  • O75023()