Lgr4/GPR48 Antibody

Immunohistochemistry-Paraffin: Lgr4/GPR48 Antibody [NLS1631] - Anti-GPR48 / LGR4 antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry-Paraffin: Lgr4/GPR48 Antibody [NLS1631] - Analysis of anti-GPR48 / LGR4 antibody with human brain neurons.

Immunohistochemistry-Paraffin: Lgr4/GPR48 Antibody [NLS1631] - Analysis of anti-GPR48 / LGR4 antibody with human brain, glioblastoma.

Immunohistochemistry-Paraffin: Lgr4/GPR48 Antibody [NLS1631] - Anti-GPR48 / LGR4 antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Product Discontinued

Lgr4/GPR48 Antibody Summary

• Immunogen: Synthetic 16 amino acid peptide from N-terminal extracellular domain of human LGR4.
• Localization: Integral membrane protein.
• Specificity: Human LGR4. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Predicted Species: Mouse (94%), Rabbit (94%), Primate (94%), Monkey (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: LGR4
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 5 - 12 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Orangutan (94%), Marmoset (94%), Rat (88%), Elephant (88%), Canine (81%), Bovine (81%), Panda (81%), Porcine (81%).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for Lgr4/GPR48 Antibody

• GPR48
• GPR48G protein-coupled receptor 48
• G-protein coupled receptor 48
• leucine-rich repeat containing G protein-coupled receptor 4
• Lgr4

Background

GPR48 is an Orphan-A GPCR with an unknown ligand. GPR48 expression has been documented in human brain, adrenal, heart, kidney, liver, skeletal muscle, ovary, pancreas, placenta, prostate, spleen, stomach, testis, thyroid, and spinal cord.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Lgr4/GPR48 Antibody (NLS1631)(1)

Publication using NLS1631

• Shannon KB. IQGAP Family Members in Yeast, Dictyostelium, and Mammalian Cells. Int J Cell Biol 2012-01-01 [PMID: 22505937]

Bioinformatics

• Gene Symbol: LGR4
• Entrez:
  • 55366(Human)
  • 107515(Mouse)