Laforin/EPM2A Antibody (S84-37) [FITC]

Product Discontinued

Laforin/EPM2A Antibody (S84-37) [FITC] Summary

• Immunogen: Fusion protein amino acids 1-331 (full-length) of human Laforin. Rat: 90% identity (296/327 amino acids identical). Mouse: 89% identity (295/327 amino acids identical)
• Localization: Endoplasmic Reticulum
• Specificity: Detects approx 40kDa.
• Predicted Species: Rat (90%). Backed by our 100% Guarantee.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: EPM2A
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Protein G purified

Alternate Names for Laforin/EPM2A Antibody (S84-37) [FITC]

• EC 3.1.3.16
• EC 3.1.3.48
• epilepsy, progressive myoclonus type 2, Lafora disease (laforin)
• epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
• EPM2
• EPM2A
• Lafora PTPase
• Laforin
• LAFPTPase
• LD
• LDE
• MELF

Background

EPM2A encodes a dual-specificity phosphatase that associates with polyribosomes. The encoded protein may be involved in the regulation of glycogen metabolism. Mutations in this gene have been associated with myoclonic epilepsy of Lafora. Alternative splicing results in multiple transcript variants. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: EPM2A