Laforin/EPM2A Antibody (523435) [Janelia Fluor® 549]

• Reactivity: Hu
• Applications: WB
• Clone: 523435
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Janelia Fluor 549

Laforin/EPM2A Antibody (523435) [Janelia Fluor® 549] Summary

• Immunogen: E. coli-derived recombinant human Laforin/EPM2A
  Met1-Leu331
  Accession # AAH70047
• Specificity: Detects human Laforin/EPM2A in Western blots.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: EPM2A
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Laforin/EPM2A Antibody (523435) [Janelia Fluor® 549]

• EC 3.1.3.16
• EC 3.1.3.48
• epilepsy, progressive myoclonus type 2, Lafora disease (laforin)
• epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
• EPM2
• EPM2A
• Lafora PTPase
• Laforin
• LAFPTPase
• LD
• LDE
• MELF

Background

EPM2A encodes a dual-specificity phosphatase that associates with polyribosomes. The encoded protein may be involved in the regulation of glycogen metabolism. Mutations in this gene have been associated with myoclonic epilepsy of Lafora. Alternative splicing results in multiple transcript variants. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: EPM2A