Kv3.4 Antibody (S72-16) [Alexa Fluor® 405]

Product Discontinued

Kv3.4 Antibody (S72-16) [Alexa Fluor® 405] Summary

• Immunogen: Synthetic peptide amino acids 175-192 of rat Kv3.4
• Epitope: (GDEAGDDERELALQRLGP)
• Localization: Membrane
• Specificity: Detects approx 70kDa (100kDa in brain due to glycosylation).
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: KCNC4
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein G purified

Alternate Names for Kv3.4 Antibody (S72-16) [Alexa Fluor® 405]

• HKSHIIIC
• K+ channel subunit
• KSHIIIC
• KV3.4
• MGC126818
• potassium voltage-gated channel subfamily C member 4
• potassium voltage-gated channel, Shaw-related subfamily, member 4
• Voltage-gated potassium channel subunit Kv3.4

Background

Kv3.4 (Potassium voltage gated channel subfamily C member 4) belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: KCNC4
• Entrez:
  • 684516(Rat)
• Uniprot:
  • Q63734(Rat)