KOR Antibody (387310) [Unconjugated]

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KOR was detected in immersion fixed paraffin-embedded sections of human brainstem (medulla) using 15 µg/mL Mouse Anti-Human KOR Monoclonal Antibody (Catalog # MAB38951) overnight at 4 °C. Before incubation with the ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clone
387310
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

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Catalog# & Formulation Size Price

KOR Antibody (387310) [Unconjugated] Summary

Immunogen
NS0 mouse myeloma cell line transfected with human KOR
Met1-Val380
Accession # P41145
Specificity
Detects human KOR. Stains human KOR transfectants but not irrelevant transfectants.
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
OPRK1
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 8-25 ug/mL
Publications
Read Publication using
MAB38951 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for KOR Antibody (387310) [Unconjugated]

  • kappa opioid receptor
  • kappa-type opioid receptor
  • KOR
  • K-OR-1
  • KOR-1
  • Opiate receptor, kappa-1
  • opioid receptor, kappa 1
  • OPRK
  • OPRK1
  • Oprk2
  • R21

Background

Kappa Opioid Receptor (KOR) is a 45 kDa 7TM opioid receptor that is primarily expressed in the central nervous system and peripheral visceral pain sensory nerves. Following ligation by dynorphin peptides, KOR signaling induces analgesia, dysphoria, diuresis, and increased feeding desire. KOR also exerts neuroprotective and anti-inflammatory effects. Human KOR shares 94% amino acid sequence identity with mouse and rat KOR.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for KOR Antibody (MAB38951)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: IHC-P.


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IHC-P
(1)
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Human
(1)
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Bioinformatics

Gene Symbol OPRK1
Uniprot