KOR Antibody (387310) [Alexa Fluor® 488]

• Reactivity: Hu
• Applications: IHC
• Clone: 387310
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 488

KOR Antibody (387310) [Alexa Fluor® 488] Summary

• Immunogen: NS0 mouse myeloma cell line transfected with human KOR
  Met1-Val380
  Accession # P41145
• Specificity: Detects human KOR. Stains human KOR transfectants but not irrelevant transfectants.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for KOR Antibody (387310) [Alexa Fluor® 488]

• kappa opioid receptor
• kappa-type opioid receptor
• KOR
• K-OR-1
• KOR-1
• Opiate receptor, kappa-1
• opioid receptor, kappa 1
• OPRK
• OPRK1
• Oprk2
• R21

Background

Kappa Opioid Receptor (KOR) is a 45 kDa 7TM opioid receptor that is primarily expressed in the central nervous system and peripheral visceral pain sensory nerves. Following ligation by dynorphin peptides, KOR signaling induces analgesia, dysphoria, diuresis, and increased feeding desire. KOR also exerts neuroprotective and anti-inflammatory effects. Human KOR shares 94% amino acid sequence identity with mouse and rat KOR.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.