KOR Antibody (1123A) [Alexa Fluor® 405]

• Reactivity: Rt
• Applications: ICC/IF
• Clone: 1123A
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Alexa Fluor 405

KOR Antibody (1123A) [Alexa Fluor® 405] Summary

• Additional Information: Recombinant Monoclonal Antibody.
• Immunogen: Rat KOR N-terminal synthetic peptide
  Accession # P34975
• Specificity: Detects rat KOR in direct ELISAs.
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for KOR Antibody (1123A) [Alexa Fluor® 405]

• kappa opioid receptor
• kappa-type opioid receptor
• KOR
• K-OR-1
• KOR-1
• Opiate receptor, kappa-1
• opioid receptor, kappa 1
• OPRK
• OPRK1
• Oprk2
• R21

Background

KOR is a 45 kDa 7TM opioid receptor that is primarily expressed in the central nervous system and peripheral visceral pain sensory nerves. Following ligation by dynorphin peptides, KOR signaling induces analgesia, dysphoria, diuresis, and increased feeding desire. KOR also exerts neuroprotective and anti-inflammatory effects. Human KOR shares 94% amino acid sequence identity with mouse and rat KOR.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.