KDM2B Antibody

Immunohistochemistry-Paraffin: KDM2B Antibody [NBP2-99310] - Staining of human KDM2B in human skin with rabbit polyclonal antibody at 1:1000 dilution.

Product Discontinued

KDM2B Antibody Summary

• Description: This antibody can be stored at 2C to 8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.
• Immunogen: Produced in rabbits immunized with a synthetic peptide corresponding to the center region of the Human KDM2B.
• Predicted Species: Mouse (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: KDM2B
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:500-1:2000
  • Immunohistochemistry-Paraffin 1:500-1:2000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 0.2 um filtered solution in PBS
• Preservative: No Preservative
• Purity: Antigen Affinity-purified

Alternate Names for KDM2B Antibody

• [Histone-H3]-lysine-36 demethylase 1B
• CXXC2
• CXXC2F-box protein FBL10
• CXXC-type zinc finger protein 2
• FBL10
• F-box and leucine-rich repeat protein 10JEMMA (Jumonji domain, EMSY-interactor, methyltransferase motif) protein
• F-box protein FBL10
• FBXL10
• JHDM1B
• JHDM1BF-box/LRR-repeat protein 10
• JmjC domain-containing histone demethylation protein 1B
• jumonji C domain-containing histone demethylase 1B
• Jumonji domain-containing EMSY-interactor methyltransferase motif protein
• KDM2B
• lysine (K)-specific demethylase 2B
• lysine-specific demethylase 2B
• NDY1
• PCCX2
• PCCX2EC 1.14.11.27
• protein containing CXXC domain 2
• Protein JEMMA
• Protein-containing CXXC domain 2

Background

KDM2B encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: KDM2B