KCNN2 Antibody - BSA Free

Immunohistochemistry-Paraffin: KCNN2 Antibody [NBP3-14382] - Immunohistochemistry of formalin-fixed, paraffin-embedded human kidney after heat-induced antigen retrieval.

• Reactivity: Hu, Ca, Eq, Ha, Pm, Pm-Or, Pm
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

KCNN2 Antibody - BSA Free Summary

• Description: Product can be stored undiluted at 4C for up to 1 month.
• Immunogen: Synthetic 18 amino acid peptide from C-Terminus of human KCNN2.
• Epitope: C-Terminus
• Specificity: Human KCNN2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Predicted Species: Monkey (100%), Primate (100%), Equine (94%), Canine (94%), Hamster (94%), Orangutan (100%). Backed by our 100% Guarantee.
• Clonality: Polyclonal
• Host: Rabbit
• Gene: KCNN2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
• Application Notes: .

Reactivity Notes

Expected reactivity based on percent sequence identity: Marmoset, Rat, Bat (89%), Mouse, Porcine (83%)

Packaging, Storage & Formulations

• Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for KCNN2 Antibody - BSA Free

• hSK2
• KCa2.2
• KCa2.2SKCA2
• KCNN2
• potassium intermediate/small conductance calcium-activated channel, subfamilyN, member 2
• SK2apamin-sensitive small-conductance Ca2+-activated potassium channel
• SKCa 2
• SKCa2
• small conductance calcium-activated potassium channel protein 2

Background

Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. This gene is a member of the KCNN family of potassium channel genes. Two transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: KCNN2