KALRN Antibody

Immunohistochemistry-Paraffin: KALRN Antibody [NBP1-02585] - Staining of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

Product Discontinued

KALRN Antibody Summary

• Immunogen: Synthetic peptide from human KALRN.
• Specificity: A synthetic peptide corresponding to amino acids 1591-1605 (KEP LQL PKT PAK QRN) of human HAPIP/KALRN protein.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: KALRN
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:1000
  • Immunohistochemistry 5 ug/ml
  • Immunohistochemistry-Paraffin 5 ug/ml

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.09% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Protein G purified

Alternate Names for KALRN Antibody

• ARHGEF24
• DUETFLJ16443
• duo
• EC 2.7.11.1
• FLJ12332
• FLJ18623
• HAPIP
• huntingtin-associated protein interacting protein (duo)
• Huntingtin-associated protein-interacting protein
• kalirin
• kalirin, RhoGEF kinase
• Protein Duo
• serine/threonine kinase with Dbl- and pleckstrin homology domains
• Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain
• TRADFLJ18196

Background

Duet is a TRIO/TRAD serine/threonine kinase with Dbl-Homology (DH) and Pleckstrin-Homology (PH) domains. Duet protein was localized to actin-associated cytoskeletal elements, suggesting a role in the cytoskeleton-dependent cell function.Huntington's disease is an inherited neurodegenerative disease which occurs when the widely expressed protein huntingtin contains an expanded glutamine repeat. HAPIP protein binds to HAP1, which is a huntington binding protein that may function in vesicle trafficking.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: KALRN
• Entrez:
  • 8997(Human)
• Uniprot:
  • O60229(Human)