Kallikrein 12 Antibody [Unconjugated]

Images

 
There are currently no images for Kallikrein 12 Antibody (AF3095).

Every product we sell is backed by Novus' 100% Guarantee. If you have used this product, please submit your images and reviews to earn reward points.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC, IP
Clonality
Polyclonal
Host
Sheep
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

View Available Formulations
Catalog# & Formulation Size Price

Kallikrein 12 Antibody [Unconjugated] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human Kallikrein 12
Ala18-Asn248
Accession # Q9UKR0
Specificity
Detects human Kallikrein 12 in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant human (rh) Kallikrein 8, rhKallikrein 10, rhKallikrein 11, and rhKallikrein 15 is observed.
Source
N/A
Isotype
IgG
Clonality
Polyclonal
Host
Sheep
Gene
KLK12
Purity Statement
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 5-15 ug/mL
  • Immunoprecipitation 25 ug/mL
  • Western Blot 0.1 ug/mL
Publications
Read Publication using
AF3095 in the following applications:

  • ICC
    1 publication

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Kallikrein 12 Antibody [Unconjugated]

  • DKFZp686H1078
  • EC 3.4.21
  • EC 3.4.21.-
  • Kallikrein 12
  • Kallikrein-like protein 5
  • kallikrein-related peptidase 12
  • KLK12
  • KLK-L5
  • KLKL5kallikrein-12
  • KLK-L5MGC42603

Background

Human tissue Kallikrein 12, encoded by the KLK12 gene, is a secreted serine protease that belongs to the human tissue kallikrein family. It is present in many tissues, such as salivary gland, stomach and breast. KLK12 displays trypsin-like enzymatic activity. This activity can be inhibited by Serpin F2 (R&D Systems, Catalog # 1470-PI). The physiological functions of KLK12 still remain unclear. Its expression is modulated by steroid hormones and is down‑regulated in breast cancer (2). Human KLK12 has three splice variants resulting from alternative splicing of the 3’ end. The KLK12 produced by the R&D Systems corresponds to the full-length classical form, also known as isoform 2 (1). The amino acid sequence of human KLK12 is 80%, 77%, 71% and 66% to that of bovine, canine, mouse, and rat. The recombinant human KLK12 can be autoactivated under the conditions described in the Activity Assay Protocol. The active enzyme has the N-terminal sequence of I22FNGTECGRNS.

  1. Yousef, G.M. et al. (2000) Genomics. 69:331.
  2. Yousef, G.M. and E.P. Diamandis (2001) Endocrine Rev. 22:184.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

AF7928
Species: Mu
Applications: IHC, WB
AF2008
Species: Hu
Applications: IHC, IP, WB
MAB35661
Species: Hu
Applications: IHC, IP, Neut, WB
1108-SE
Species: Hu
Applications: EnzAct
AF2625
Species: Hu
Applications: IHC, IP, Neut, WB
2626-SE
Species: Hu
Applications: EnzAct
AF1595
Species: Hu
Applications: IHC, IP, WB
H00005655-M01
Species: Hu
Applications: ELISA, ICC/IF, IHC, IHC-P, WB
DKK300
Species: Hu
Applications: ELISA
2025-SE
Species: Hu
Applications: EnzAct
AF2624
Species: Hu, Mu
Applications: IHC, IP, WB
AF2498
Species: Mu
Applications: IP, WB
NBP1-06046
Species: Hu
Applications: IHC, IHC-P, PEP-ELISA, WB
AF4055
Species: Mu
Applications: IHC, Simple Western, WB
NBP2-93612
Species: Hu, Mu, Rt
Applications: IHC, IHC-P, WB
NB100-96916
Species: Hu
Applications: Flow, ICC/IF, IHC, IHC-P, PEP-ELISA, WB
DVE00
Species: Hu
Applications: ELISA
7754-BH/CF
Species: Hu
Applications: BA
AF3095
Species: Hu
Applications: WB, IHC, IP

Publications for Kallikrein 12 Antibody (AF3095)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: ICC.


Filter By Application
ICC
(1)
All Applications
Filter By Species
Human
(1)
All Species

Reviews for Kallikrein 12 Antibody (AF3095) (0)

There are no reviews for Kallikrein 12 Antibody (AF3095). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for Kallikrein 12 Antibody (AF3095) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional Kallikrein 12 Products

Bioinformatics Tool for Kallikrein 12 Antibody (AF3095)

Discover related pathways, diseases and genes to Kallikrein 12 Antibody (AF3095). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for Kallikrein 12 Antibody (AF3095)

Discover more about diseases related to Kallikrein 12 Antibody (AF3095).
 

Pathways for Kallikrein 12 Antibody (AF3095)

View related products by pathway.

PTMs for Kallikrein 12 Antibody (AF3095)

Learn more about PTMs related to Kallikrein 12 Antibody (AF3095).

Blogs on Kallikrein 12

There are no specific blogs for Kallikrein 12, but you can read our latest blog posts.
Omicron Variant Antibodies

Customers Who Bought This Also Bought

Contact Information

Download our Western Blot eHandbook

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our Kallikrein 12 Antibody [Unconjugated] and receive a gift card or discount.

Bioinformatics

Gene Symbol KLK12
Uniprot