Kallikrein 10 Antibody [DyLight 680]

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Goat
• Conjugate: DyLight 680

Kallikrein 10 Antibody [DyLight 680] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human Kallikrein 10
  Ala34-Asn276
  Accession # O43240
• Specificity: Detects human Kallikrein 10 in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 5% cross-reactivity with recombinant human (rh) rhKallikrein 3, rhKallikrein 5, and rhKallikrein 11 is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: KLK10
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Kallikrein 10 Antibody [DyLight 680]

• breast normal epithelial cell associated serine protease
• EC 3.4.21
• EC 3.4.21.-
• EC 3.4.21.74
• Kallikrein 10
• kallikrein-related peptidase 10
• KLK10
• NES1
• NES1kallikrein-10
• Normal epithelial cell-specific 1
• Protease serine-like 1
• PRSSL1protease, serine-like, 1

Background

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: KLK10